AT406 (SM-406) TGOLD

AT406 (SM-406) TGOLDAT406 (SM 406) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP BIR3, cIAP1 BIR3 and cIAP2 BIR3 with Ki of 66. 4 nM, 1. 9 nM, and 5. 1 nM, 50 to 100 fold higher affinities than the Smac AVPI peptide. Phase 1.

Corning These 2L PYREX(r) round bottom boiling flasks have full length outer 24/40 Standard Taper joints

Corning These 92mL PYREX® standard weighing bottles have an external 45/12 Standard Taper joint style opening

The unit has a 29/42 inner Standard Taper joint and a 71/60 outer Standard Taper joints at the top and bottom

Cyanide as hydrocyanic acid (HCN) is released from cyanide complexes by means of a reflux-distillation and absorbed in a scrubber containing a sodium hydroxide solution

used to treat high blood pressure and congestive heart failure

Tygon® is a registered trademark of Norton Co

c-Src and c-Abl with IC50 of 0

Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM

Raltitrexed is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth

CDK1/7 and GSK-3

Specific design features include: - COP

multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM