Midostaurin (PKC412) FrostedMidostaurin (pkc412) is a multi targeted kinase inhibitor, including PKC? ? ?, Syk, Flk 1, Akt, PKA, c Kit, c Fgr, c Src, FLT3, PDFR? and VEGFR1 2 with IC50 ranging from 80 500 nM.
Somatostatin Acetate is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones
Asunaprevir is an orally bioavailable inhibitor of the hepatitis C virus enzyme serine protease NS3 that is necessary for protein processing required for viral replication
Hygromycin B
It is less potent to CDK5/6 and also inhibits GSK3
mediatated by activation of
anti-cancer activity and wound-healing activity
shown to inhibit PI3K
originally identified as a blocker of receptor-mediated calcium entry
it is used as a cough suppressant
which is the first potent
Acipimox is a niacin derivative used as a hypolipidemic agent
>100-fold selectivity over PKA