LRRK2-IN-1 Membr

LRRK2-IN-1 MembrLRRK2 IN 1 is a potent and selective LRRK2 inhibitor with IC50 of 6 nM and 13 nM for LRRK2 (G2019S) and LRRK2 (WT), respectively.

Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity

with EC50 of ~50 nM and 5

Bumetanide (Bumex) is a loop diuretic of the sulfamyl category to treat heart failure

4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines

also known as diaminodiphenyl sulfone (DDS)

N6-methyladenosine (m6A) is a base modified analog of adenosine and is found as a minor nucleoside in natural RNAs

17 nM in human and rabbit

mostly PI3K

Ozagrel is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet

a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis

Diethylstilbestrol is a synthetic nonsteroidal estrogen

with Ki of 15 nM