PF-477736 DesiccatorPF 477736 is a selective, potent and ATP competitive Chk1 inhibitor with Ki of 0. 49 nM in a cell free assay and also inhibits VEGFR2, Aurora A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~100 fold selectivity for Chk1 than Chk2. Phase 1.
000-fold selectivity over AT2
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM in a cell-free assay
Cladribine is an adenosine deaminase inhibitor for U266
and little activity to Abl
Pimasertib (AS-703026) is a highly selective
Corning These 4L PYREX® serum bottles are designed especially for handling and storing sterile culture media and sera where stability of the glass is of prime importance
Acitretin is a second generation retinoid used for psoriasis
Due to the heavy wall
which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0
Iniparib (BSI-201) is a PARP1 inhibitor with demonstrated effectiveness in triple-negative breast cancer (TNBC)
greater than 8-fold selective against HDAC3 and no inhibition to HDAC1
mostly for Flt3 with IC50 of 6
